The best Side of cees dekker
The best Side of cees dekker
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Nanotechnology provides A variety of chances to lead to biology. In this article I'll existing illustrations where nanofabrication – the ability to make confined constructions with Proportions at will – is utilised to look at the biophysics of solitary molecules and cells. I'll current some examples from our lab:
Our team scientific tests bacterial cell division and it is aiming to constitute a ‘base up biology’ in synthetic cells that can autonomously divide. Our most important fascination lies in cell division, chromatin structure, and spatial Regulate.
, Groningen researchers current the outcome in their initiatives for making labs extra sustainable and provide methods for other labs.
2007, first authentic-time detection of strand exchange in homologous recombination by RecA; discovery of a small persistence length of ends of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
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The coiled-coil on the human Rad50 DNA restore protein contains precise segments of improved adaptability
We form germs into types that deviate from their natural phenotype. Specifically, I'll exhibit our capability to shape Are living E. coli micro organism into novel designs including rectangles, squares, triangles and circles.
He also identified time to jot down a number of guides, deliver Just about forty thousand tweets and lead An effective investigate group at Delft College of Technology. ‘It doesn’t truly feel like do the job’, he states. ‘I’m just terribly curious.’
Comprehending essential procedures regulating the spatial and dynamic organisation on the DNA in live cells.
At this time, we also recognized that it should be possible to use an individual semiconducting carbon nanotube to create a transistor — and we established out to make it. We stretched individual semiconducting nanotubes throughout metallic electrodes and utilized the underlying silicon substrate for a gate electrode, establishing the basic 3-terminal structure of a field-influence transistor (Fig.
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Cees Dekker is Distinguished College Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) ceesdekker chromosome structure, especially SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is surely an elected member of your KNAW and fellow into the APS as well as IOP.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is displayed.